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ESTUDIO WHI, REVISTA DE MENOPAUSIA, SALUD, REVISTAS MÉDICAS. Actualidad Inmediata Debido a la importancia de esta investigación y al impacto en. WHI. Progestin. Estrogen. Tibolone. Cardiovascular disease. Tromboembolic disease . Boletín de la Asociación Española para el Estudio de la Menopausia, . Los trastornos de la menopausia pueden ser evitados y combatidos Sin embargo, recientes estudios, como el estudio WHI, han puesto en duda los beneficios.

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What is important is the best possible etudio to preventive medicine in a mid-aged woman. Ipriflavone Multicenter European Fracture Study. Clinical effects of a standardized soy extract in postmenopausal women: Evaluation of soy phytoestrogens for the treatment of hot flashes in breast cancer survivors: Editorial JAMA ; 3: To reassess the need wui HRT after four years of therapy and not recommend HRT for the sole purpose of preventing chronic disease, such as cardiovascular disease or osteoporosis as other alternatives are available To promote the use of additional and alternative non-hormonal strategies for maintaining health and preventing disease in symptom free women of middle age and beyond.

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J Clin Endocrinol Metab, 86pp. National Institutes of Health, Diabetes Care, 25pp.

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Maturitas, 42pp. It seems that the recommendations of the WHI writing group are mainly focused on public rather than individual health, since they say that, even small individual risks over time, and on a population-wide basis, add up to ten’s of thousands of those serious adverse health events and becomes an important public health concern.

Clin Invest Gin Obst, 30pp. Menopause, 6pp.

Maturitas, 44pp. To improve our services and products, menppausia use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer menppausia. Background Placebo controlled randomised clinical trials are considered to be the gold standards to assess the real risks and benefits of chronic treatments. Risks and benefits of estrogen plus progestin in healthy postmenopausal women.


Dietary phytoestrogens and their effect on bone: Our main goal, as attending physicians of postmenopausal women, is the maintenance of their health and the primary and secondary prevention of the diseases, which are more prevalent after age 50 [ 13 ]. Urinary excretion of phytoestrogens and risk of breast cancer among Chinese women menopausix Shangai.

High dietary phytoestrogen intake is associated with higher bone mineral density in postmenopausal but non premenopausal women.

Results from WHI and HERS II – Implications for women and the prescriber of HRT

Preventing a woman from the benefits of a sound postmenopausal hormone therapy because of the fear of rare side effects does not seem to be satisfactory Medicine Cancer Causes Control, 13pp. Strengths of WHIMS-Y include balance in baseline risk factors between treatment groups, standardized and masked data collection, and high rates of retention and on-trial adherence and exposure.

High quality observational studies may extend evidence over a wider population and are likely to be dominant in the identification of harms [ 8 ]. Risk and benefits of estrogen plus progestin in healty postmenopausal women. J Clin Oncol, 18pp. The recommendation of WHI Committee is that continuous estrogen plus progestin should not be used even for the primary prevention of heart disease, and that they only should be used for the relief of vasomotor symptoms!

Beneficial effects of soy phytoestrogen intake in postmenopausal women with type 2 diabetes. Influence of estrogen plus progestin on breast cancer and mammography in healty postmenopausal women. Obstet Gynecol,pp. Flaxseed dietary supplement versus hormone replacement therapy in hypercholesterolemic menopausal women. Is there a menopausal medicine? You can change the settings or obtain more information by clicking here.


However, interim reports on women on estrogens alone did not show adverse CV or breast cancer crossing the predetermined safety boundaries, and this part of the trial thus continues.

We present the study rationale estuddio design. The Nurses’ Health Study and studies from Europe, where estradiol is the commonly prescribed form of estrogen, suggest that the estrogen at lower doses may confer similar benefit” [ 15 ] Luckily one has nowadays an ample choice of strategies and drugs hormonal and non-hormonal that enable a conscientious physician to do his best to restore the confidence of those women who have sought his help.

It would suggest that if mehopausia were treated menopwusia one year there would be less than one woman with an adverse effect. The increased risk of breast cancer became apparent only after the fourth year of treatment.

Although there are no results yet from this ongoing study, it already carries an important message. Role of the gut flora in toxicity and cancer, pp. These cancers were invasive. Clin Endocrinol Oxf56pp. Int J Cancer,pp.


Which clinical studies provide the best evidence? Failure of estrogen plus progestin therapy for prevention. Maturitas, 45 whu, pp. Thus this fixed excessive dose for older women does not necessarily reflect optimal good clinical practice and is not followed by any responsible gynaecologist. Br J Nutr, 89pp. The Women’s Health lnitiative lnvestigators. The order of magnitude of the relative risks is impressive.