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Erythema elevatum diutinum (EED) is a rare, chronic dermatosis that is characterized by red–violet to red–brown papules, plaques, and. Erythema elevatum diutinum (EED) is a chronic form of leukocytoclastic vasculitis consisting of violaceous, red-brown, or yellowish papules. Erythema elevatum diutinum. Authoritative facts about the skin from DermNet New Zealand.

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Review [Erythema elevatum diutinum. From Wikipedia, the free encyclopedia.

Antineutrophil cytoplasmic antibodies of IgA class may be helpful as a marker of disease, and Immunoelectrophoresis can also be used to identify possible gammopathies. Nevertheless, the most widely accepted theory is that previous and repeated exposure to bacterial infections, particularly streptococcal ones, may trigger an immunological reaction that culminates in an outbreak of skin lesions.

Eritema elevatum diutinum | Actas Dermo-Sifiliográficas

Erythema elevatum diutinum and HIV infection: Although the etiology of EED is unknown, circulating immune complexes, with repeated deposition, associated inflammation, and partial erritema are thought to represent the underlying pathogenesis. Erythema elevatum diutinum EED is a rare type of necrotising vasculitis that is characterised by red, purple, brown or yellow papules raised spotplaquesor nodulesfound on the backs of the hands, other extensor surfaces overlying joints, and on the buttocks.


Erutema site uses cookies to provide, maintain and improve your experience. Over time, the infiltrate contains more histiocytes and granulation tissue, and spindle cell eleevatum may be seen. View All Subscription Options. The cause of EED is not well understood, but it is thought to be secondary to immune complex deposition in dermal blood vessels, which results in complement fixation and subsequent inflammation.

Erythema, Elevatum Diutinum – StatPearls – NCBI Bookshelf

Erythema elevatum diutinum in association with coeliac disease. By using this site, you agree to the Terms of Use and Privacy Policy. EED is a chronic and progressive skin disease that may last as long as 25 years. It occurs equally in men and women. A rare dermatosis with a broad spectrum of associated illnesses]. The erythrocyte sedimentation rate in patients with EED is often elevated.

Consequently, even though the association of EED with HIV infection is infrequent, laboratory investigation for this virus should be requested in conventional cases, and especially in cases of atypical and exacerbated clinical manifestations.

Cutaneous vasculitis Skin signs of rheumatic disease Other websites: Over the course of the disease, collagen is deposited around the vessels and, occasionally, cholesterol crystals are detected. A chronic leukocytoclastic vasculitis typified by a distinctive clinical pattern.

April 13, Accepted: Click here for patient related inquiries. Review Erythema elevatum eritemw In addition, antiretroviral therapy should be introduced in these cases, in association with dapsone, which is the drug of eriteka for the treatment of EED.


Today, one-and-a-half years after the HIV-positive blood test and the beginning of antiretroviral therapy, the patient has not had any recurrence of the skin lesions.

Erythema elevatum diutinum is a form of vasculitis. Erythema gyratum repens Necrolytic migratory duitinum.

Erythema elevatum diutinum – a case successfully treated with colchicine. It has been described as a paraneoplastic syndrome. J Am Acad Dermatol. Home About Us Advertise Amazon.

Eritema elevatum diutinum as a differential diagnosis of rheumatic diseases: case report.

Report of three cases. Images hosted on other servers: The condition is benign in nature but may be associated with infections, hematologic abnormalities, autoimmune diseases, or other conditions. Dapsone, a sulfonamide antibiotic that impairs neutrophil chemotaxis and function, is the most effective treatment agent, but relapse is common upon discontinuation.

Epub Sep Previous treatment with topical corticosteroids had been unsuccessful. Si continua navegando, consideramos que acepta su uso. There is no significant mortality associated with EED.

Trunk is usually spared. Firm brown tumors on extensor surfaces of extremities.